Did you know that your gut plays a major role in how well your thyroid functions? Your gut microbiome can have a significant impact on thyroid health!
One of the key components in this relationship are short-chain fatty acids (SCFAs), which are produced by the bacteria in your gut.
In this blog, we’ll dive into the importance of SCFAs, how they support your thyroid, and why getting a gut microbiome test could be a game changer for those dealing with thyroid conditions.
What Are SCFAs?
SCFAs are fatty acids that are produced when specific beneficial bacteria in your gut break down fibre from the foods you eat. Some of the most common SCFAs include acetate, propionate, and butyrate. These compounds are powerful little molecules that have far-reaching effects on your body.
While SCFAs are often discussed in relation to gut health, their impact goes far beyond just your digestive system. They influence everything from immune function to hormone regulation, and thyroid health!
There are two key factors required for optimal SCFA production.
1 – Eating enough, and the correct types of dietary fibre
2 – Having the correct balance of bacteria in your gut to optimally ferment these fibres in SCFAs
The Link Between SCFAs and Thyroid Health
Your thyroid plays a critical role in regulating metabolism, energy levels, and overall hormonal balance. When it isn’t functioning propelly, such as in cases of hypothyroidism (an underactive thyroid) or hyperthyroidism (an overactive thyroid – it can lead to a range of symptoms like fatigue, weight gain or loss, and mood changes.
SCFAs have been shown to support thyroid health in several ways:
1 – Enhancing Thyroid Hormone Conversion: The thyroid gland produces hormones, but some of these hormones need to be converted in your body to become active. For instance, T4 (thyroxine) must be converted into T3 (triiodothyronine) for it to be used effectively.
SCFAs, particularly butyrate, help support the enzymes involved in this conversion process, ensuring your thyroid hormones are working at their best [2].
2 – Regulating Inflammation: SCFAs help reduce inflammation in the body. Chronic inflammation can disrupt thyroid function, potentially leading to conditions like Hashimoto’s thyroiditis. By promoting anti-inflammatory responses, SCFAs help protect the thyroid from damage [1].
3 – Supporting Gut Health: A healthy gut is essential for hormone balance. SCFAs nourish the cells in the gut lining, keeping your digestive system strong and functioning properly. A well-functioning gut ensures that your body can absorb nutrients that are critical for thyroid health, such as iodine and selenium [3].
4 – Improving Insulin Sensitivity: SCFAs also help with insulin regulation. Since thyroid function is closely linked to metabolism, improving insulin sensitivity through SCFAs can lead to better overall metabolic health, which in turn supports healthy thyroid function [4].
Why a Gut Microbiome Test Matters for Thyroid Health
As you can see, there’s a direct connection between a healthy gut microbiome and a healthy thyroid. If you’re struggling with thyroid issues, improving the balance of bacteria in your gut could be a useful strategy.
Gut for you’s simple stool swab test can give you valuable insight into the types of bacteria living in your digestive system and how they may be influencing your thyroid health.
With this information, you can take targeted actions to improve your gut health and, in turn, support your thyroid.
Restoring a healthy gut microbiome balance may offer therapeutic benefits for individuals with thyroid disorders.
Gut for you have created a gut microbiome test that can unlock 50+ key health insights from the gut.
From a small swab of the toilet roll, we are able to identify more than 2000 bacteria in the gut. By referencing more than 90 published studies in each test report, we are able to identify if imbalances are present, and what they might mean for your health.

Once we have analysed the stool sample, we recommend a personalised diet. Using the concept of starving the bacteria you need less of, and feeding the bacteria you need to increase – we can naturally rebalance the gut microbiome and bring it to a more optimal state.

Conclusion
The connection between gut health and thyroid function is more important than many people realise. SCFAs are critical in supporting a healthy thyroid, reducing inflammation, helping hormone conversion, and maintaining gut integrity.
If you’re struggling with thyroid health, exploring your gut microbiome through testing can provide valuable insights and lead to effective changes that benefit both your thyroid and overall well-being.
References
1. Zeng, H., et al. (2020). Short-chain fatty acids and gut microbiota in thyroid diseases. Frontiers in Endocrinology, 11, 595158. doi:10.3389/fendo.2020.595158
2. Tuncer, I., et al. (2019). The role of butyrate in thyroid hormone conversion. Journal of Clinical Endocrinology & Metabolism, 104(3), 898-908. doi:10.1210/jc.2018-01804
3. Mathews, P., et al. (2021). Gut microbiome and thyroid function: A complex relationship. Thyroid Research, 14(1), 23. doi:10.1186/s13044-021-00095-3
4. Li, M., et al. (2022). *Short-chain fatty acids and insulin sensitivity: Potential mechanisms and